diff --git a/esphome/components/ble_client/sensor/__init__.py b/esphome/components/ble_client/sensor/__init__.py
index efe4bf0e9a..4aa6a92ba5 100644
--- a/esphome/components/ble_client/sensor/__init__.py
+++ b/esphome/components/ble_client/sensor/__init__.py
@@ -67,7 +67,7 @@ async def to_code(config):
             var.set_service_uuid32(esp32_ble_tracker.as_hex(config[CONF_SERVICE_UUID]))
         )
     elif len(config[CONF_SERVICE_UUID]) == len(esp32_ble_tracker.bt_uuid128_format):
-        uuid128 = esp32_ble_tracker.as_hex_array(config[CONF_SERVICE_UUID])
+        uuid128 = esp32_ble_tracker.as_reversed_hex_array(config[CONF_SERVICE_UUID])
         cg.add(var.set_service_uuid128(uuid128))
 
     if len(config[CONF_CHARACTERISTIC_UUID]) == len(esp32_ble_tracker.bt_uuid16_format):
@@ -87,7 +87,9 @@ async def to_code(config):
     elif len(config[CONF_CHARACTERISTIC_UUID]) == len(
         esp32_ble_tracker.bt_uuid128_format
     ):
-        uuid128 = esp32_ble_tracker.as_hex_array(config[CONF_CHARACTERISTIC_UUID])
+        uuid128 = esp32_ble_tracker.as_reversed_hex_array(
+            config[CONF_CHARACTERISTIC_UUID]
+        )
         cg.add(var.set_char_uuid128(uuid128))
 
     if CONF_DESCRIPTOR_UUID in config:
@@ -108,7 +110,9 @@ async def to_code(config):
         elif len(config[CONF_DESCRIPTOR_UUID]) == len(
             esp32_ble_tracker.bt_uuid128_format
         ):
-            uuid128 = esp32_ble_tracker.as_hex_array(config[CONF_DESCRIPTOR_UUID])
+            uuid128 = esp32_ble_tracker.as_reversed_hex_array(
+                config[CONF_DESCRIPTOR_UUID]
+            )
             cg.add(var.set_descr_uuid128(uuid128))
 
     if CONF_LAMBDA in config: