diff --git a/esphome/components/mcp3221/mcp3221_sensor.cpp b/esphome/components/mcp3221/mcp3221_sensor.cpp
index 2164bc32ad..674be499c3 100644
--- a/esphome/components/mcp3221/mcp3221_sensor.cpp
+++ b/esphome/components/mcp3221/mcp3221_sensor.cpp
@@ -26,7 +26,7 @@ float MCP3221Sensor::sample() {
     return NAN;
   }
 
-  uint16_t value = (data[0] << 8) | data[1];
+  uint16_t value = encode_uint16(data[0], data[1]);
   float voltage = value * this->reference_voltage_ / 4096.0f;
 
   return voltage;
diff --git a/esphome/components/mcp3221/sensor.py b/esphome/components/mcp3221/sensor.py
index a06a0676bc..c32698fdd3 100644
--- a/esphome/components/mcp3221/sensor.py
+++ b/esphome/components/mcp3221/sensor.py
@@ -12,8 +12,6 @@ from esphome.const import (
 AUTO_LOAD = ["voltage_sampler"]
 DEPENDENCIES = ["i2c"]
 
-# CONF_CONTINUOUS_MODE = "continuous_mode"
-
 
 mcp3221_ns = cg.esphome_ns.namespace("mcp3221")
 MCP3221Sensor = mcp3221_ns.class_(