diff --git a/esphome/components/lora/lora.cpp b/esphome/components/lora/lora.cpp
index 874330d386..2bf593f608 100644
--- a/esphome/components/lora/lora.cpp
+++ b/esphome/components/lora/lora.cpp
@@ -151,6 +151,8 @@ void Lora::check_for_message_() {
   std::string buffer;
   std::vector<uint8_t> data;
   bool pin_data_found = false;
+  if (!this->available())
+    return;
   ESP_LOGD(TAG, "Reading serial");
   while (this->available()) {
     uint8_t c;