diff --git a/esphome/components/sen5x/sen5x.cpp b/esphome/components/sen5x/sen5x.cpp
index 42951d6089..c90880bc9f 100644
--- a/esphome/components/sen5x/sen5x.cpp
+++ b/esphome/components/sen5x/sen5x.cpp
@@ -201,13 +201,19 @@ void SEN5XComponent::setup() {
           ESP_LOGE(TAG, "Failed to read RHT Acceleration mode");
         }
       }
-      if (this->voc_tuning_params_.has_value())
+      if (this->voc_tuning_params_.has_value()) {
         this->write_tuning_parameters_(SEN5X_CMD_VOC_ALGORITHM_TUNING, this->voc_tuning_params_.value());
-      if (this->nox_tuning_params_.has_value())
+        delay(20);
+      }
+      if (this->nox_tuning_params_.has_value()) {
         this->write_tuning_parameters_(SEN5X_CMD_NOX_ALGORITHM_TUNING, this->nox_tuning_params_.value());
+        delay(20);
+      }
 
-      if (this->temperature_compensation_.has_value())
+      if (this->temperature_compensation_.has_value()) {
         this->write_temperature_compensation_(this->temperature_compensation_.value());
+        delay(20);
+      }
 
       // Finally start sensor measurements
       auto cmd = SEN5X_CMD_START_MEASUREMENTS_RHT_ONLY;
diff --git a/esphome/components/sen5x/sen5x.h b/esphome/components/sen5x/sen5x.h
index f306003a82..6d90636a89 100644
--- a/esphome/components/sen5x/sen5x.h
+++ b/esphome/components/sen5x/sen5x.h
@@ -41,8 +41,8 @@ struct GasTuning {
 };
 
 struct TemperatureCompensation {
-  uint16_t offset;
-  uint16_t normalized_offset_slope;
+  int16_t offset;
+  int16_t normalized_offset_slope;
   uint16_t time_constant;
 };
 
@@ -70,27 +70,33 @@ class SEN5XComponent : public PollingComponent, public sensirion_common::Sensiri
   void set_voc_algorithm_tuning(uint16_t index_offset, uint16_t learning_time_offset_hours,
                                 uint16_t learning_time_gain_hours, uint16_t gating_max_duration_minutes,
                                 uint16_t std_initial, uint16_t gain_factor) {
-    voc_tuning_params_.value().index_offset = index_offset;
-    voc_tuning_params_.value().learning_time_offset_hours = learning_time_offset_hours;
-    voc_tuning_params_.value().learning_time_gain_hours = learning_time_gain_hours;
-    voc_tuning_params_.value().gating_max_duration_minutes = gating_max_duration_minutes;
-    voc_tuning_params_.value().std_initial = std_initial;
-    voc_tuning_params_.value().gain_factor = gain_factor;
+    GasTuning tuning_params;
+    tuning_params.index_offset = index_offset;
+    tuning_params.learning_time_offset_hours = learning_time_offset_hours;
+    tuning_params.learning_time_gain_hours = learning_time_gain_hours;
+    tuning_params.gating_max_duration_minutes = gating_max_duration_minutes;
+    tuning_params.std_initial = std_initial;
+    tuning_params.gain_factor = gain_factor;
+    voc_tuning_params_ = tuning_params;
   }
   void set_nox_algorithm_tuning(uint16_t index_offset, uint16_t learning_time_offset_hours,
                                 uint16_t learning_time_gain_hours, uint16_t gating_max_duration_minutes,
                                 uint16_t gain_factor) {
-    nox_tuning_params_.value().index_offset = index_offset;
-    nox_tuning_params_.value().learning_time_offset_hours = learning_time_offset_hours;
-    nox_tuning_params_.value().learning_time_gain_hours = learning_time_gain_hours;
-    nox_tuning_params_.value().gating_max_duration_minutes = gating_max_duration_minutes;
-    nox_tuning_params_.value().std_initial = 50;
-    nox_tuning_params_.value().gain_factor = gain_factor;
+    GasTuning tuning_params;
+    tuning_params.index_offset = index_offset;
+    tuning_params.learning_time_offset_hours = learning_time_offset_hours;
+    tuning_params.learning_time_gain_hours = learning_time_gain_hours;
+    tuning_params.gating_max_duration_minutes = gating_max_duration_minutes;
+    tuning_params.std_initial = 50;
+    tuning_params.gain_factor = gain_factor;
+    nox_tuning_params_ = tuning_params;
   }
   void set_temperature_compensation(float offset, float normalized_offset_slope, uint16_t time_constant) {
-    temperature_compensation_.value().offset = offset * 200;
-    temperature_compensation_.value().normalized_offset_slope = normalized_offset_slope * 100;
-    temperature_compensation_.value().time_constant = time_constant;
+    TemperatureCompensation temp_comp;
+    temp_comp.offset = offset * 200;
+    temp_comp.normalized_offset_slope = normalized_offset_slope * 10000;
+    temp_comp.time_constant = time_constant;
+    temperature_compensation_ = temp_comp;
   }
   bool start_fan_cleaning();
 
diff --git a/esphome/components/sen5x/sensor.py b/esphome/components/sen5x/sensor.py
index 392510e417..4bc4a138a3 100644
--- a/esphome/components/sen5x/sensor.py
+++ b/esphome/components/sen5x/sensor.py
@@ -88,6 +88,15 @@ GAS_SENSOR = cv.Schema(
     }
 )
 
+
+def float_previously_pct(value):
+    if isinstance(value, str) and "%" in value:
+        raise cv.Invalid(
+            f"The value '{value}' is a percentage. Suggested value: {float(value.strip('%')) / 100}"
+        )
+    return value
+
+
 CONFIG_SCHEMA = (
     cv.Schema(
         {
@@ -151,7 +160,9 @@ CONFIG_SCHEMA = (
             cv.Optional(CONF_TEMPERATURE_COMPENSATION): cv.Schema(
                 {
                     cv.Optional(CONF_OFFSET, default=0): cv.float_,
-                    cv.Optional(CONF_NORMALIZED_OFFSET_SLOPE, default=0): cv.percentage,
+                    cv.Optional(CONF_NORMALIZED_OFFSET_SLOPE, default=0): cv.All(
+                        float_previously_pct, cv.float_
+                    ),
                     cv.Optional(CONF_TIME_CONSTANT, default=0): cv.int_,
                 }
             ),