diff --git a/notmuch-reply.c b/notmuch-reply.c
index 6c15536c..3c5b253e 100644
--- a/notmuch-reply.c
+++ b/notmuch-reply.c
@@ -282,6 +282,69 @@ add_recipients_from_message (GMimeMessage *reply,
     return from_addr;
 }
 
+
+static const char *
+guess_from_received_header(notmuch_config_t *config, notmuch_message_t *message)
+{
+    const char *received,*primary;
+    char **other;
+    char *by,*mta,*ptr,*token;
+    char *domain=NULL;
+    char *tld=NULL;
+    const char *delim=". \t";
+    size_t i,other_len;
+
+    received = notmuch_message_get_header (message, "received");
+    by = strstr(received," by ");
+    if (by && *(by+4)) {
+	/* we know that there are 4 characters after by - either the 4th one
+	 * is '\0' (broken header) or it is the first letter of the hostname 
+	 * that last received this email - which we'll use to guess the right
+	 * from email address
+	 */
+	mta = strdup(by+4);
+	if (mta == NULL)
+	    return NULL;
+	/* After the MTA comes its IP address (or HELO response) in parenthesis.
+	 * so let's terminate the string there
+	 */
+	if ((ptr = strchr(mta,'(')) == NULL) {
+	    free (mta);
+	    return NULL;
+	}
+	*ptr = '\0';
+	/* Now extract the last two components of the MTA host name
+	 * as domain and tld
+	 */
+	token = mta;
+	while ((ptr = strsep(&token,delim)) != NULL) {
+	    if (*ptr == '\0')
+		continue;
+	    domain = tld;
+	    tld = ptr;
+	}
+	if (domain) {
+	    /* recombine domain and tld and look for it among the configured
+	     * email addresses
+	     */
+	    *(tld-1) = '.';
+	    primary = notmuch_config_get_user_primary_email (config);
+	    if (strcasestr (primary, domain)) {
+		free(mta);
+		return primary;
+	    }
+	    other = notmuch_config_get_user_other_email (config, &other_len);
+	    for (i = 0; i < other_len; i++)
+		if (strcasestr (other[i], domain)) {
+		    free(mta);
+		    return other[i];
+		}
+	}
+	free(mta);
+    }
+    return NULL;
+}
+
 static int
 notmuch_reply_format_default(void *ctx, notmuch_config_t *config, notmuch_query_t *query)
 {
@@ -312,9 +375,13 @@ notmuch_reply_format_default(void *ctx, notmuch_config_t *config, notmuch_query_
 	g_mime_message_set_subject (reply, subject);
 
 	from_addr = add_recipients_from_message (reply, config, message);
-
-	if (from_addr == NULL)
-	    from_addr = notmuch_config_get_user_primary_email (config);
+	
+	if (from_addr == NULL) {
+	    from_addr = guess_from_received_header (config, message);
+	    if (from_addr == NULL) {
+	        from_addr = notmuch_config_get_user_primary_email (config);
+	    }
+	}
 
 	from_addr = talloc_asprintf (ctx, "%s <%s>",
 				     notmuch_config_get_user_name (config),